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level: Level 1 of ANTIPROTOZOAL

Questions and Answers List

level questions: Level 1 of ANTIPROTOZOAL

Question	Answer
Highly prevalent in Third World Countries	Malaria, Amoebiasis Giardiasis Trichomoniasis Toxoplasmosis P. carinii pneumonia (PCP)
Drugs for Amoeba (Entamoeba Histolytica) in 1) Intestinal and Extraintestinal 2) 2nd group, Intestinal form	1) Emetine Dehydroemetine Metronidazole Chloroquine 2) Paromomycin Iodoquinol (8-hydroxyquinoline derivative) Carbasone (Arsenical compound) Diloxanide
1 Drug for Balantidiasis 2 Drug for Gardiasis	1) Tetracycline (best) ---- Metronidazole Iodoquinol 2) Furazolidone Metronidazole Quinacrine
1 Drug for Trichomoniasis (trophozoite) 2 Drug of choice for PCP (Pneumocystis carinii Pneumonia)	1 Oral Metronidazole 2 Sulfamethoxazole (Sulfonamide) AND Trimethoprim Others: pentamidine, atovaquone, trimetrexate
1 Cause blindness in neonates 2 Yellow malodorous frothy vaginal discharge	1 TOXOPLASMA GONDII 2 Trichomonas
1 Drug of choice for TOXOPLASMA GONDII 2 TOXOPLASMA GONDII can also cause:	1 Sulfadiazine + Pyrimethamine 2 - Mental retardation - microcephaly
1 (West African) Sleeping sickness 2 (East African) Sleeping sickness 3 (South American sleeping sickness, Chagas disease)	1) T. gambiense 2) - T. rhodesiense - T. congolense 3) T. cruzi
Kala-azar disease is caused by?	Leishmania donovanii
1 Drug for Sleeping Sickness but causes long and short term prophylaxis 2 Major asset in controlling sleeping sickness but toxic	1) Suramin 2 Nifurtimox
1) 1st marketed for treatment of T. vaginalis; Treatment for disease caused by anaerobic bacteria 2) Treatment for asymptomatic carriers of E. histolytica; Obtained in CDC in Atlanta, Georgia	1 Metronidazole (Flagyl) 2) Diloxanide (Furamide or Eutamide)