Estás en modo de exploración. debe iniciar sesión para usar MEMORY

level: level 2 (Azole Antifungal Agents PART)

Questions and Answers List

Question	Answer
1 Imidazole rings 2 AZOLES	1) miconazole, clotrimazole 2) 1,2,4-Triazole rings
1 Azole Antifungal Agents are used for __ 2 Azole inhibits __	1 Superficial and Systemic infections 2 Ergosterol (Fungal cell membrane)
S/E: gynecomastia (Enlarged Boobs) , decreased libido, impotence, menstrual irregularities, hepatoxicity Imidazole Systemic fungal infections: orally Topical: cream and shampoo	Ketoconazole (Nizoral)
Triazole ring Requires acidic medium Absorption is enhanced by foods Systemic fungal infections More effective and better than Ketoconazole (NO SIDE EFFECTS)	Itraconazole (Sporanox)
Triazole ring Oral and IV Excellent penetration to CSF DOC for cryptococcal meningitis Excellent bioavailability	Fluconazole (Diflucan)
Systemic fungal infection Mucocuntaneous candidiasis Creams, lotions, powder, spray, suppositories	Miconazole (Monistat)
Topically for tinea infections and and candidiasis Lotion, cream, tablets Extremely stable> 5 years Highly protein bound	Clotrimazole (Mucelex, Lotrimin)
1 Used for Opportunistic Microorganisms in Low Immunocompromised individuals like AIDS 2 Name is LY30336 during clinical trials	1 Voriconazole 2 (Anidulafungin) Eraxis
Much better than Voriconazole Oral suspension For severe immunocompromised patients	(Posaconazole) Noxafil
Inhibits Inositol Phosphoryl Ceramide Under the name: IPC Synthase 55 during clinical trials	Aureobasidin A (TaKaRa)