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level: Introduction to Medical Parasitology

Questions and Answers List

level questions: Introduction to Medical Parasitology

QuestionAnswer
It enables the parasite to move in a circular mannerUndulating membrane
It enables the parasite to move in a circular mannerUndulating membrane
It enables the parasite to move in a circular mannerUndulating membrane
It enables the parasite to move in a circular mannerUndulating membrane
It enables the parasite to move in a circular mannerUndulating membrane
It enables the parasite to move in a circular mannerUndulating membrane
Retortamonas intestinalis': Habitat? Developmental stage? Infective stage? Mode of transmission?Large intestine
the living together of unlike organisms. It may also involve protection or other advantages to one or both organisms.Symbiosis
a symbiotic relationship in which two species live together and one species benefits from the relationshipCommensalism
A parasite living inside the bodyEndoparasite
parasite living outside the bodyEctoparasite
presence of an endoparasite in a hostInfection
presence of an ectoparasite on a hostInfestation
it is found in an organ which is not its usual habitatErratic
they need a host at some stage of their life cycle to complete their development and to propagate their species.obligate parasites
may exist in a free-living state or may become parasitic when the needfacultative parasite
A parasite, which establishes itself in a host where it does not ordinarily liveaccidental or incidental parasite
Parasites that remains on or in the body of the host for its entire life,Permanent Parasite
A parasite that lives on the host only for a short period of time.temporary parasite
free-living organism that passes through the digestive tract without infecting the host.Spurius parasite
one in which the parasite attains sexual maturity.Definitive host
harbors the asexual or larval stage of the parasite.Asexual host
one in which the parasite does not develop further to later stages.However, the parasite remains alive and is able to infect another susceptible host.Paratenic Host
They allow the parasite’s life cycle to continue and become additional sources of human infection.Reservoir host
responsible for transmitting the parasite from one host to another.Vectors
transmits the parasite only after the latter has completed its development within the host.Biologic Vector
only transports the parasite.Mechanical vector
harbors a particular pathogen without manifesting any signs and symptoms.Carrier
the process of inoculating an infective agent,Exposure
connotes the establishment of the infective agent in the host.Infection
the period between infection and evidence of symptomsIncubation period
period between infection or acquisition of the parasite and evidence or demonstration of infection.biologic incubation period
when an infected individual becomes his own direct source of infection.Autoinfection
The most common sources for parasitic infection are:contaminated soil and water.
Examples of parasites from night soil or infected soilAscaris lumbricoides, Trichuris trichiura, Strongyloides stercoralis, and hookworm.
Examples of parasites from contaminated water (cysts)cysts of amebae or flagellates, as well as cercariae of Schistosoma
which may contain the infective stage of the parasite, as exemplified by a number of?trematode and cestode infections
Consumption of undercooked or raw freshwater fish are present with what type of parasites?intestinal and liver fluke infections.
Raw crabs are considered a delicacy in areas where ____is endemic.paragonimiasis
raw Bullastra snails are associated with ___ infection.Artyfechinostomum malayanum
Mosquitoes are vectors of ?malaria and filaria parasites.
Triatoma bugs are carriers of ____ causing Chagas disease.Trypanosoma cruzi
Sand flies (e.g., Phlebotomus spp.) are the natural vectors of all types of ____.Leishmania.
the infected person himself is the source of infection is seen in the life cycles of Capillaria philippinensis, Enterobius vermicularis, Hymenolepis nana, and Strongyloides stercoralis.Autoinfection w
Majority of infections with cestodes, trematodes, and intestinal protozoans are foodborne: such as?Taenia solium, Taenia saginata, and Diphyllobothrium latum from eating food harboring the infective larval stages;
are parasites from drinking water contaminated with cysts;Entamoeba histolytica and Giardia lamblia
Are parasites through ingesting raw or improperly cooked freshwater fish containing infective larvae.Clonorchis, Opistorchis, and Haplorchis
Skin penetration is another route of transmission. ___ enter via exposure of skin to soil,Hookworms and Strongyloides
__-- enter skin via water.Schistosoma species
congenital transmission example.Toxoplasma gondii trophozoites can cross the placental barrier during pregnancy.
the parasites may be transmitted through mother’s milk.Ancylostoma and Strongyloides,
Other ways of acquiring the infection include inhalation of airborne eggs of ___Enterobius
sexual intercourse as in the case ofTrichomonas vaginalis.
study of patterns, distribution, and occurrence of diseaseEpidemiology
infection appearing in a population in a given period of time.Incidence
the number (usually expressed as percentage) of individuals in a population estimated to be infected with a particular parasite species at a given time.Prevalence
the percentage of individuals in a population infected with at least one parasite.Cumulative prevalence
burden of infection which is related to the number of worms per infected person.Intensity of infection
morbidity.Clinical consequences of infections or diseases that affect an individual’s well-being
use of anthelminthic drugs in an individual or a public health program.Deworming
refers to the number (usually expressed as a percentage) of previously positive subjects found to be egg negative on examination of a stool or urine sample using a standard procedure at a set time after deworming.Cure rate
the percentage fall in egg counts after deworming based on examination of a stool or urine sample using a standard procedure at a set time after the treatment.Egg reduction rate (ERR)
involves individual-level deworming with selection for treatment based on a diagnosis of infection or an assessment of the intensity of infection, or based on presumptive grounds.Selective treatment
group-level deworming where the (risk) group to be treated (without prior diagnosis) may be defined by age, sex, or other social characteristics irrespective of infection status.Targeted treatment
population-level deworming in which the community is treated irrespective of age, sex, infection status, or other social characteristics.Universal treatment
the regular, systematic, large-scale intervention involving the administration of one or more drugs to selected population groups with the aim of reducing morbidity and transmission of selected helminth infections.Preventive Chemotherapy
the proportion of the target population reached by an intervention.Coverage
the effect of a drug against an infective agent in ideal experimental conditions and isolated from any context.Efficacy
measure of the effect of a drug against an infective agent in a particular host, living in a particular environment with specific ecological, immunological, and epidemiological determinants.Effectiveness
Entamoeba histolytica's: Habitat? Effect to host? Developmental stage? Infective stage? Mode of transmission?Colon Pathogenic Cyst and Trophozoite Cyst Ingestion/ fecal oral route
Entamoeba coli's: Habitat? Effect to host? Developmental stage? Infective stage? Mode of transmission?Colon Non-pathogenic Cyst and Trphozoite Cyst Ingestion/ fecal oral route
Endolimax nana's: Habitat? Effect to host? Developmental stage? Infective stage? Mode of transmission?Colon Non-pathogenic Cyst and Trophozoite Cyst Ingestion/ fecal oral route
Iodamoeba butschii's: Habitat? Effect to host? Developmental stage? Infective stage? Mode of transmission?Colon Non- pathogenic Cyst and Trophozoite Cyst Ingestion/ fecal oral route
Entamoeba gingivalis': Habitat? Effect to host? Developmental stage? Infective stage? Mode of transmission?Buccal cavity/ oral cavity Non-pathogenic Trophozoite Trophozoite Oral contact
Parasite for head louse?Pediculus humanus capitis
Parasite for body louse?Pediculus humanus coporis
Reservoir host for bever?Gardia lamblia
Reservoir host for sheeps and cattlesFasciola hepatica
It is the parasite ascaris for dogsToxocara canis
It is the parasite ascaris for cats?Toxocara cati
Protozoan stage that is best visualized using iodine?Cyst
Protozoan stage that is best visualized using permanent stains?Trophozoite
Process of encystation?Trophozoite --> Pre cyts --> Cyst
Process of excystation?cyst --> metacystic trophozoite --> trophozoite
Entamoeba histolytica's: Size of cyst Number of nuclei in cyst Chromatodial bodies Size of trophozoite Karyosome Cytoplasmic inclusions10-2-0 um 1-4 cigar or bar shape 12-60 um Indistinct and central Ingested RBC and Bacteria
Entamoeba coli Size of cyst Number of nuclei in cyst Chromatodial bodies Size of trophozoite Karyosome Cytoplasmic inclusions10-35 um 1-8 Splintered ends w/ broomstick appearance 15-50 um Eccentric (not in the middle) Bacteria, food vacuoles and debri
Endolimax nana's: Size of cyst Number of nuclei in cyst Chromatodial bodies Size of trophozoite Karyosome Cytoplasmic inclusions5-10 um 4 Small spherical 6-12 um Irregular or blot like Bacteria, food vacuoles and debri
Iodamoeba butschii's: Size of cyst Number of nuclei in cyst Chromatodial bodies Size of trophozoite Karyosome Cytoplasmic inclusions5-20 um 1 No chromatoidal bodies but w/ large glycogen mass 8-20 um Surrounded w/ achromatic granules (Sunflower type) Bacteria, food vacuoles, and debri
Entamoeba gingivalis': Size of cyst Number of nuclei in cyst Chromatodial bodies Size of trophozoite Karyosome Cytoplasmic inclusions5-20 um Unable to produce cyst 10-20 um Food vacuoles and WBC
Regarded as the smallest intestinal protozoa, often referred to as CROSS-EYED CYSTEntamoeba nana
Iodine cystIodamoeba butschii
With “Bull’s eye karyosome”; Tissue invading – can produce flask shaped ulcersEntamoeba histolytica
Most common form of extraintestinal amebiasisHepatic
With long finger like pseudopodiaEntamoeba histolytica
Regarded as “small race-histolytica”Entamoeba hartmanni
Morphologically closest to Entamoeba histolytica, can be differentiated fro E. histolytica thru immunoassays or thru PCREntamoeba dispar Used to be Entamoeba hartmanni
Naegleri fowleri's: Regarded as an? Infective stage is Causes Thermophilic organism Acquired thru Diagnostic stage: Cyst is NOT SEEN in brain tissues; cyst has ____ wall Trophozoites :Facultative, free leaving, ameboflagelate Ambeoid trophozoite Primarily amebic meningoencephalitis diving or swimming in stagnant water trophozoite in CSF & Brain Tissues; flagellated forms occasionally in CSF double and smooth outer wall ameboid trophozoite & flagellated trophozoite
Acanthamoeba species Causes ? Infective stage: Diagnostic stages: Cyst has ____OUTER wall Culturable in? Trophozoite has spine like process called_____; SLOWLY MOTILE1. Granulomatous amebic encephalitis 2. Amebic keratitis (contact lense wearer) 3. Skin lesions Cyst & trophozoite Cyst and trophozoites in tissues wrinkled outer wall Non Nutrient Agar seeded w/ E. coli ACANTHOPODIA
Type of entamoeba that shows progressive and directional motilityEntamoeba histolytica
Type of entamoeba that shows sluggish and non directional motilityEscherichia coli
Balamuthia mandrillaris Isolated from ü Infective stages: ü Can enter thru 1) ___ 2)___ ü Cyst & trophozoites in tissues; cyst issoil and dust or from autopsy specimens of infected humans & animals cyst and trophozoite nasal passages and ulcerated or broken skin 10-25 um with DOUBLE CYST WALL
Gardia lamblia's: Habitat? Developmental stage? Infective stage? Mode of transmission?Small intestine Cyst and Trophozoites Cyst Ingestion
Chilomastix mesnili Habitat? Developmental stage? Infective stage? Mode of transmission?Large intestine Cyst and Trophozoite Cyst Ingestion
Retortamonas intestinalis': Habitat? Developmental stage? Infective stage? Mode of transmission?Large intestine Cyst and trophozoites Cyst Ingestion
Enteromas hominis': Habitat? Developmental stage? Infective stage? Mode of transmission?Large intestine Cyst and Trophozoite Cyst Ingestion
Dientamoeba fragilis': Habitat? Developmental stage? Infective stage? Mode of transmission?Large intestine Trophozoite Trophozoite Ingestion
Pentatrichomonas hominis': Habitat? Developmental stage? Infective stage? Mode of transmission?Large intestine Trophozoite Trophozoite Ingestion
Trichomonas vaginalis': Habitat? Developmental stage? Infective stage? Mode of transmission?Gut Trophozoite Trophozoite Sexual contact
Trichomonas tenax's: Habitat? Developmental stage? Infective stage? Mode of transmission?Bucal gut Trophozoite Trophozoite Oral contact
Giardia lamblia's: Cyst Shape/ size # of nuclei Equipped with ____ and has a pair of?Ovoid; 8-15 um 4 oblique axostyle (/) and has a pair of parabasal body
Chilomastix mesnili's: Cyst Shape/ size # of nuclei Curved fibril alongside cytosome, usually referred to as a?Lemon or nipple; 7-10 um 1
Enteromas hominis': Cyst Shape/ size # of nuclei Resembles cyst of?Ellipsoidal; 6-8 um 4 in binoculate condition
Retoramonas intestinalis': Cyst Shape/ size # of nuclei Fibril extebd above nucleus giving aOvoid, Pyriform; 4-7 um 1 Bird's beak appearance
Giardia lamblia"s Trophozoite Number of nuclei # of flagella Sucking disk; old man w/ glasses, has a __ motility and bilaterally__2 8 falling leaf motility symmetrical
Chilomastix mesnili's: Trophozoite Number of nuclei # of flagella Cork screw, has a __ motility1 3 external and 1 internal spiral jerky
Enteromonas hominis': Trophozoite Number of nuclei # of flagella1 3 anterior, 1 posterior
Retortomonas intestinalis Trophozoite Number of nuclei # of flagella1 1 anterior, 1 posterior
Dientamoeba fragilis Previously ___; unable to produce Trophozoite is ___ um W/ multiple ___ pseudopodia Karyosome is often fragmented and is often referred to as?antamoeba, cyst 5-15 um multiple hyaline leaf like Tetrakaryosome
Equipped w/ undulating membrane and 5 glagella Cannot produce cyst Axostyle extends beyond the bodyPentatrichomonas hominis Trichomonas vaginalis Trichomonas tenax
Largest trophozoite?Trichomonas vaginaliS
Smallest trophozoite?Trichomonas tenax
May cause Gay bowel syndromeGardia lamblia
May cause excretion of fats in fecesGardia lamblia
What are the developmental stages of blood and tissue haemoflagellates?Amastigote (leishamnia) --> Promastigote (leptomonas)--> Epimastigote (crithidia)--> Trypomastigote (trypanosoma)
Amastigote/ leishmania is: ___ shaped with nucleus and kinetoplast but ____ membrane and ____Oval no undulating flagellum
Promastigote/ leptomonas are: ____ with nucleus , kinetoplast and flagellum but no undulating membraneelongated
Epimastigote are: with nucleus kinetoplast, flagellum and undulating membrane Kinetoplast is ___ the nucleus ___than promastigoteAbove
Trypomastigote are W/ nucleus Kinetoplast Flagellum Undulating membrane Kinetoplast is ___ the nucleusBelow
It enables the parasite to move in a circular mannerUndulating membrane
Leishmania donovani's: Vector Developmental stage Infective stage to man Disease Caused Affected organPhlebotomous spp. (Sand flies) Amastigote (Develop in man) Promastigote (Develop in vector) Promastigote Kala-Azar Fever/ Visceral leishmaniasis, Dumdum fever, Death Fever, Tropical splenomegaly, Black Disease Visceral organ
Lesihmania braziliensis': Vector Developmental stage Infective stage to man Disease Caused Affected organPhlebotomous spp. (Sand flies) Amastigote (Man) Promastigote (Vector) Promastigote Muco-cutaneous, Leishmaniasis Espunida, Ulta, Chiclero Ulcer Mucous membrane
Leishmania tropica's: Vector Developmental stage Infective stage to man Disease Caused Affected organPhlebotomous spp. (Sand flies) Amastigote (Man) Promastigote (Vector) Promastigote Cutaneous Leishmaniasis, Delhi ulcer, Baghad Boil, Aleppo
May cause anemia, hepatosplenomegaly & blackening of skinLeishmania donovani
May produce widespread lesions that leave ugly scar on healingLeishmania tropica
May produce leprosy like or highly disfiguring lesions mainly on the faceLeishmania braziliensis
Skin biopsy____tissue biopsy____to search amastigote
Examination of lymph node, BM , liver aspirate--
Lesihmania spp. are ___parasitesIntracellular
Trypanosoma brucei gambiense: Vector Infective stage to man Diagnostic stage Disease Caused Type of parasiteGlossina spp. (tse tse flies) Metacylic trypanosome -- West African Sleeping Sickness External parasite
Trypanasoma brucei rhodesiense Vector Infective stage to man Diagnostic stage Disease Caused Type of parasiteGlossina spp (tse tse) -- -- East African Sleeping Disease External parasite
Trypanosoma cruzi Vector Infective stage to man Diagnostic stage Disease Caused Type of parasiteReduviid, Triatoma, Panstrongylus spp. Metacyclic trypanosome Amastigote, Trypomastigote New World Trypanosomiasis, South American Chaga's DIsease Intracelullar parasite
African Sleeping Sickness or Old World Trypanosomiasis: Lesion at bite site: Blood invasion will cause Lymph node will CNSTrypanosome chancre Fever enlarge (Winterbottom sign) Kerandel's sign
Type of African Sleeping Sickness or Old World Trypanosomiasis that is rapidly fatalTrypanosoma brucei rhodesiense
Type of African Sleeping Sickness or Old World Trypanosomiasis that has longer courseTrypanosoma brucei gambience
Chaga's Disease/ South American Trypanosomiasis/ New World Trypanomiasis Lesion at bite site Unilateral conjunctivitis or orbital edema calledCHAGOMA Romana's Sign
Common parasite of pigs; habitat is the large intestine and regarded as the largest intestinal protozoaBalantidium coli
Balantidium coli's cyst has macronucleus ____ for vegetation and a micronucleus ___ for reproduction Trophozoites shows___motility with cytostome and __ Causes ? Can be detected under ___due to large size under microscope Will not produce lesions outisde ____kidney shaped nucleus and spherical nucleus directional tumblin Balantidiasis, balintidial dysentery
What are the five plasmodium spp.?P. falciparum P. ovale P. vivax P. malariae P. knowlesi
What is the gold standard for the detection of malaria?Thick and thin smear udner OIO