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level: Level 1

Questions and Answers List

Question	Answer
too much hemolysis that the hepatocytes cannot keep up in conjugating B1 leading to accumulation of UB in the serum	Hemolytic Jaundice
Indirect Bilirubin/B1	Unconjugated Bilirubin
Conjugated Bilirubin	B2/Direct Bilirubin
Congenital Hyperbilirubinemia- excess deficit leads to accumulation of B1	crigler-najjar type 1
Congenital Hyperbilirubinemia- conjugation deficit leads to accumulation of B1 since UDP GT is absent	crigler-najjar type 1
Similar to Dubin-Johndon syndrome but is autosomal dominant (genetic disease)	Rotor Syndrome
T/F Obstructive Jaundice causes an increase in conjugated bilirubin	TRUE
Found in the Endoplasmic Reticulum for processing of drugs	CYT P450
T/F Hepatocellular Jaundice causes decreased AST and ALT	FALSE
T/F Neonatal Jaundice is caused by underdeveloped liver and low UDP GT during the first 4 weeks of neonates	TRUE
The less fatal type of Crigler Najjar; colorless bile	Type 2`
Less specific aminotransferase	AST
SGPT	ALT
sensitive aminotransferase	AST
SGOT	AST
In obstructive jaundice urobilinogen is absent	TRUE
Protein transporter of nonsoluble bilirubin	Albumin
green pigment (linear structure)	Biliverdin
Bilirubin is color ________	red-orange
In this solution both UB and CB reacts to diazotized sulfanilic acid to form red azodipyrroles	Methanol
Cannot be synthezised without vit. K	Prothrombin II, VII, IX, X
In Kramer's rule, which level and which part of the infant should be jaundiced to cause high concern	Level 4 - arms and legs