| What can be a secondary condition of arthiritis | Secondary sjogren’s syndrome |
| What oral implication can arthiritis have | Periodontitits |
| Tx of arthritits | NSAIDs
Disease-modifying antirheumatic drugs (e.g. methotrexate)
Steroids
Biologic therapies (e.g. anti-TNF therapy)
Destructive effects of TNF |
| TNF MABs | Adalimumab Infliximab |
| Uveitis: | inflammatory of the uveal tract (blue layer) |
| Tx of arthritis | NSAIDs
Disease modifying anti-rheumatic drugs, e.g. methotrexate for psoriatic arthritis (PsA)
Steroids
Biological therapies (e.g. anti-TNF therapy) |
| SLE patients present with | Hair loss oral ulcerations and connnective tissue disease vasculitits |
| Raynauds | Blood vessels narrow reducing flow to hands which become cold and white |
| livedo reticularis | Mottles reticules vascular pattern that appears like a lace purplish discolouration of the lower extremities |
| Scleroderma affects | Skin thickening
Difficulty opening mouth
Raynaud’s phenomenon
Internal organ disease:
Lungs
Kidney
Gut |
| Skin changes in scleroderma | Inflammatory
Indurative than atrophic phase
Oedema
Tightening
Thickening
Waxy feel
Loss of function in hands, arms, legs
Chest involvement
Telangectasia |
| Vasculitits describe | Temperotal arteritis or giant cell ateritis (GCA)
Prevalence 200/100,000 aged >50
Headache
Scalp tenderness
Jaw claudication
Fatigue
Visual loss |
| Granulomatosis with polyangiitis (GPA) (Wegeners) is- | Bloody nasal discharge
Nasal collapse
Stridor
Cough and haemoptysis
Renal involvement |
| Pagets disease- describe | maxilla more than mandible can cause hypercementosis- tx with bisphosphonates |
| What two drugs can cause MRONJ | Bisphosphonates and denosomab |
| TMJ pain can be caused by | OA
RA
Ankylosing spondylitis and psoriatic arthritis
Juvenile idiopathic arthritis ( up to 50% of children with polyarticular disease) |
| Mouth ulcers can be caused by | Arthridites- reactive arthritis |
| Connective tissue diseases and vasculitides | Behcets disease
SLE |
