level: Cardiac pharma
Questions and Answers List
level questions: Cardiac pharma
| Question | Answer |
|---|---|
| Cardiac | Pharmacology |
| Blood vessels are almost exclusively controlled by | sympathetic nervous system |
| Phenylephrine, midodrine | Alpha 1 agonist |
| Doxazosin | Alpha 1 antagonist |
| Clonidine | Alpha 2 agonist |
| Dobutamine | beta 1 agonist |
| Salbutamol | beta 2 agonist |
| Mirabegron | Beta 3 agonist |
| Metoprolol | Beta 1 antagonist |
| Adrenaline is a beta agonist used for: | Asystole |
| What is dobutamine and what is it used for | Beta 1 agonists used to treat cariogenic shock |
| Salbutamol and its uses | Selective beta 2 agonists for asthma and delay of premature labour |
| Problems with salbutamol | Acts on beta 2 receptors causing vasodilation which initiates the baroreceptor reflex which increases HR and can cause tachycardia and arrythmias |
| What is salmeterol | Longer lasting salbutamol for more severe asthma |
| Phenylephrine alpha agonist | vasoconstriction |
| Doxazosin alpha 1 | Causes vasodilation to treat hypertension and raynaud's syndrome |
| Beta blockers e.g. proranolol beta 1&2 metoprolol beta 1 and at | Negative chronotropic actions decreasing work done by the heart and anit-platelet aggregation |
| Carvedilol | Mixed alpha and beta adrenoreceptor antagonist |
| Other uses of antagonist | hypertension (doxaszosin) |
| tyramine, ephedrine, amphetamine act as indirect | sympatheticomimetics |
| Phenelzine and iproniazd | MAO blockers |
| 2 main subtypes | MAO A MAO B |
| Selegiline | Selective MAO b inhibitor |
| Entacapone | catechol o-methyltransferase |
| Corticosteroids split into | Glucocorticoids and mineralcorticoids |
| Corticostreroids are synthesied in the | adrenal medulla |
| What is our endogenous glucocorticoid | Cortisol |
| What is exogenous cortisol called | hydrocortisone |