| What does Immunopathology mean? | It's a pathology subspecialty that deal with the immune responses associated with diseases. |
| What is a "hypersensitivity reaction?" | They are undesirable reactions produced by the NORMAL immune
system |
| What is an antigen? | Any substance that triggers the immune system to produce an antibody. |
| What is an antibody? | It is a PROTEIN produced by the immune system when it is exposed to antigens. |
| What is an "Immune Complex" | It is a molecule generated by binding an:
- antigen + antibody
- antigen + antigen
- antibody + complement |
| Exposure to what triggers a Type I (Anaphylactic Type) Hypersensitivity Reaction? | An Antigen |
| True or False:
Type I (Anaphylactic Type) Hypersensitivity Reactions are always fatal? | False. Not always.
(They should probably consider seeing a doctor, regardless) |
| Characterizes a Type II Hypersensitivity Reaction (Antibody – Mediated Type)? | A hypersensitivity reaction characterized by the production of an antibody in directed at a specific cell or tissue. |
| After a blood transfusion, a patient has a reaction. What kind or type of hypersensitivity reaction is it? | Type II Hypersensitivity Reaction (Antibody – Mediated Type) |
| What characterizes a Type III Hypersensitivity Reaction (Immune Complex Disease)? | an abnormal immune response mediated by the formation of antigen-antibody aggregates called "immune complexes."
(which deposit in tissues, resulting inflammation and tissue injury) |
| Systemic lupus erthematosus (SLE) and Rheumatoid arthritis (RA) are both diseases that concern various tissues in the body. They also often have what kind/type of hypersensitivity reactions? | Type III Hypersensitivity Reaction (or, "Immune Complex Disease") |
| What characterizes a Type IV Hypersensitivity Reaction (Delayed Typed or Cell-Mediated)? | A hypersensitivity reaction mediated by sensitized T lymphocytes (white blood cells). |
| Graft rejection occurs when the recipient's immune system attacks the donated graft and begins destroying the transplanted tissue or organ. What kind/type of hypersensitivity reaction is this? | Type IV Hypersensitivity Reaction (Delayed Typed or Cell-Mediated) |
| What is Systemic Lupus Erythematosus? | Systemic Lupus Erythematosus is an autoimmune disease in which the immune system attacks its own tissues, (causing widespread inflammation and tissue damage in the affected organs). |
