level: Level 1
Questions and Answers List
level questions: Level 1
| Question | Answer |
|---|---|
| Plasma concentration at steady state | Cpss |
| Plasma concentration at time = 0 | Cp0 |
| Plasma concentration at time = t | Cpt |
| Plasma concentration | Cp |
| Max concentration | C max |
| Time to maximum concentration | T max |
| Administered amount of drug in the body | Ab |
| Fraction of drug which is bioavailable | F |
| Rate constant of drug elimination | K |
| Clearance | Cl |
| Volume distribution | Vd |
| Half life | t 1/2 |
| Area under the curve | AUC |
| As required | p.r.n |
| After meals | p.c |
| Before meals | a.c. |
| Rectal | p.r. |
| Subcutaneous | s.c. |
| Intravenous | i.v. |
| intramuscular | i.m. |
| Orally | p.o. |
| Any part of the enteric system (GI tract) | Enteral administration |
| Not enteral | Parental administration |
| Rate of Elimination and dose administered | AUC determinants |
| Fraction of dose (systemic circulation) | F |
| Absorption, 1st pass metabolism | Oral availability determinants |
| Enzymes in gut lumen and wall and in liver, pH and gastric motility and hepatic perfusion (liver damage) | 1st pass metabolism determinants |
| Both ionised so not absorbed | Strong acids and bases |